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IM-54 is a cell permeable, potent and selective inhibitor of necrosis. The compound inhibits necrosis induced by oxidative stress. IM-54 does not inhibit apoptosis induced by anticancer drugs.
| Molecular Weight | 325.4 |
| Formula | C19H23N3O2 |
| CAS Number | 861891-50-1 |
| Solubility (25°C) | DMSO: 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Mikiko Sodeoka, et al. Development of selective inhibitors of necrosis
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