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Diprotin A (Ile-Pro-Ile)

Cat. No. M7863

All AbMole products are for research use only, cannot be used for human consumption.

Diprotin A (Ile-Pro-Ile) Structure
Synonym:

Dipeptidyl peptidase IV inhibitor

Size Price Availability Quantity
5mg USD 50 In stock
10mg USD 70 In stock
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Quality Control & Documentation
Biological Activity

Diprotin A inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines. Diprotin A induces Src and vascular endothelium-cadherin phosphorylation, increasing vascular permeability in the retina. Diprotin A (Ile-Pro-Ile) also increases number of viable phenotypic long term repopulating hematopoietic stem cells when harvesting mouse bone marrow in aerobic conditions.

Chemical Information
Molecular Weight 341.45
Formula C17H31N3O4
CAS Number 90614-48-5
Form Solid
Solubility (25°C) Soluble to 10 mM in water
Storage -20°C, protect from light, dry, sealed
References

[1] Lee CS, et al. Sci Rep. Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation.

[2] Chakraborty C, et al. Cell Biochem Biophys. Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A.

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Keywords: Diprotin A (Ile-Pro-Ile), Dipeptidyl peptidase IV inhibitor supplier, Dipeptidyl Peptidase, inhibitors, activators

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