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IEM-1925 bromide

Cat. No. M41871

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IEM-1925 bromide Structure

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Quality Control & Documentation
Biological Activity

IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy.

Chemical Information
Molecular Weight 422.24
Formula C17H30Br2N2
CAS Number 258282-23-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Olga Kopach et al. Front Cell Neurosci. Inhibition of Spinal Ca(2+)-Permeable AMPA Receptors with Dicationic Compounds Alleviates Persistent Inflammatory Pain without Adverse Effects

[2] A V Zaitsev et al. J Physiol. Specific mechanism of use-dependent channel block of calcium-permeable AMPA receptors provides activity-dependent inhibition of glutamatergic neurotransmission

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