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Icerguastat (Sephin1) Carbonate, a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A).
| Molecular Weight | 258.66 |
| Formula | C9H11ClN4O3 |
| CAS Number | 1883549-35-6 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Phosphatase Products |
|---|
| CCT007093
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
| Microcystin-LR
Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| Sal003
Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. |
| β-Glycerophosphate disodium salt hydrate
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
| Rhein-8-O-β-D-glucopyranoside
Rhein-8-glucoside calcium, a anthraquinone compound isolated from EtOH extract of Saussurea lappa root. Rhein-8-glucoside calcium is an hPTP1B inhibitor with an IC50 value of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects. |
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