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Icariin

Cat. No. M5174

All AbMole products are for research use only, cannot be used for human consumption.

Icariin Structure
Synonym:

8-prenyl kaempferol 3,7-O-diglucoside

Size Price Availability Quantity
50mg USD 30 In stock
100mg USD 43 In stock
200mg USD 55 In stock
500mg USD 85 In stock
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Quality Control & Documentation
Biological Activity

Icariin is a flavonol glycoside. Icariin inhibited PDE5 and PDE4 activity with IC50 of 432 nM and 73.50 μM, respectively. Icariin is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism.

Chemical Information
Molecular Weight 676.66
Formula C33H40O15
CAS Number 489-32-7
Solubility (25°C) DMSO 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shuangqiu Wang, et al. Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

[2] Linjiang Song, et al. Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in triple-negative breast cancer

[3] Chunyang He, et al. Pharmacological effects of icariin

[4] Nagla A El-Shitany, et al. Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways

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  Catalog
Abmole Inhibitor Catalog




Keywords: Icariin, 8-prenyl kaempferol 3,7-O-diglucoside supplier, PDE, inhibitors, activators

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