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IC 87201

Cat. No. M6806

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IC 87201 Structure

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Biological Activity

IC 87201 is a inhibits binding of the NMDA receptor postsynaptic density protein 95 kDa (PSD95) to nNOS (EC50 = 23.94 μM), while not affecting the PSD95-ErbB4 interaction. Inhibits glutamate-induced cell death in cultured cortical neurons. Exhibits antinociceptive effects in inflammatory pain models in vivo. Also exhibits antidepressant-like activitiy in animal models.

Chemical Information
Molecular Weight 309.15
Formula C13H10Cl2N4O
CAS Number 866927-10-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Canals, et al. J Cereb Blood Flow Metab. Metabolic challenge to glia activates and adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves.

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Keywords: IC 87201 supplier, inhibitors, activators

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