Free shipping on all orders over $ 500

Ibuprofen Arginate

Cat. No. M8697

All AbMole products are for research use only, cannot be used for human consumption.

Ibuprofen Arginate Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Ibuprofen arginine non-steroidal anti-inflammatory compound (NSAID) the more soluble form of ibuprofen arginine. Ibuprofen, like ibuprofen and its sodium salts, inhibits COX-2, but only ibuprofen can enhance the cellular NO pathway through the synergistic delivery of NOS substrate arginine. Ibuprofen, but not sodium, Shows reversing the inhibitory effect of Cardiotoxic hormone asymmetrically dimethylarginine (ADMA) and Ng-Nitro-L-Arginin ethyl ester (L-name) acted on nitric oxide synthase (Enos & Enol) in vitro (mouse RAW264.7 macrophages and isolated mouse and rat aorta) and effectively prevented l-name-induced increases in arterial blood pressure from large in vivo anesthesia Mice (0.5 mg/kg L - the NAME; Ibuprofen arginate 114.8 μmol/kg, equivalent to 20 mg/kg L-ARG through femoral artery intubation).

Chemical Information
Molecular Weight 380.48
Formula C19H32N4O4
CAS Number 57469-82-6
Solubility (25°C) Water: 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Juan Prez Cajaraville. Ibuprofen Arginate for Rapid-Onset Pain Relief in Daily Practice: A Review of Its Use in Different Pain Conditions

[2] B Ahmetaj-Shala, et al. Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing

[3] Nicholas S Kirkby, et al. Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis

[4] Antonio Ortega-lvaro, et al. Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain

[5] Paul Desjardins, et al. Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.

Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.

NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.

Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.

Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.

  Catalog
Abmole Inhibitor Catalog




Keywords: Ibuprofen Arginate supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.