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Hypaconitine

Cat. No. M4022

All AbMole products are for research use only, cannot be used for human consumption.

Hypaconitine Structure
Size Price Availability Quantity
2mg USD 65 In stock
5mg USD 90 In stock
10mg USD 125 In stock
20mg USD 180 In stock
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Quality Control & Documentation
Biological Activity

Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism.

Chemical Information
Molecular Weight 615.72
Formula C33H45NO10
CAS Number 6900-87-4
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shu-Shong Hsu, et al. Mechanism of action of a diterpene alkaloid hypaconitine on cytotoxicity and inhibitory effect of BAPTA-AM in HCN-2 neuronal cells

[2] Jiali Gao, et al. The mechanism underlying hypaconitine-mediated alleviation of pancreatitis-associated lung injury through up-regulating aquaporin-1/TNF-α

[3] Yanke Lin, et al. Circadian Cyp3a11 metabolism contributes to chronotoxicity of hypaconitine in mice

[4] Shuilin Xie, et al. Hypaconitine-induced QT prolongation mediated through inhibition of KCNH2 (hERG) potassium channels in conscious dogs

[5] Thomas Y K Chan. Aconite poisoning

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Keywords: Hypaconitine supplier, TNF Receptor, inhibitors, activators

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