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Hydroxyhexamide

Cat. No. M9472

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Hydroxyhexamide Structure
Synonym:

(±)-Hydroxyhexamid

Size Price Availability Quantity
5mg USD 150 In stock
10mg USD 240 In stock
25mg USD 400 In stock
50mg USD 580 In stock
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Quality Control & Documentation
Biological Activity

Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.

Chemical Information
Molecular Weight 326.41
Formula C15H22N2O4S
CAS Number 3168-01-2
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yorishige Imamura, et al. Sex-dependent pharmacokinetics of S(-)-hydroxyhexamide, a pharmacologically active metabolite of acetohexamide, in rats

[2] Y Imamura, et al. Hypoglycemic effect of S(-)-hydroxyhexamide, a major metabolite of acetohexamide, and its enantiomer R(+)-hydroxyhexamide

[3] S Asada, et al. Comparative pharmacokinetics of acetohexamide and its metabolite, hydroxyhexamide in laboratory animals

[4] Y Imamura, et al. In vivo and in vitro binding of (-)-hydroxyhexamide, a major metabolite of acetohexamide, to rabbit serum

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: Hydroxyhexamide, (±)-Hydroxyhexamid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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