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Human β-defensin-2

Cat. No. M40757

All AbMole products are for research use only, cannot be used for human consumption.

Human β-defensin-2 Structure
Synonym:

HβD-2; HBD-2

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Quality Control & Documentation
Biological Activity

Human β-defensin-2 is a cysteine-rich cationic skin antimicrobial peptide (SAP) produced by epithelial cells and a member of the cationic host defense peptide (HDP) family. Antibacterial activity against Gram-negative bacteria and Candida (LD90: 25 μg/ml). Can be used in studies related to colitis.

Chemical Information
Molecular Weight 4328.20
Formula C188H305N55O50S6
CAS Number 372146-20-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Guneet K Bindra et al. Biomolecules. Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration

[2] Martyna Cieślik et al. Cells. Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

[3] Michael Järvå et al. Sci Adv. Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

[4] J M Schröder et al. Int J Biochem Cell Biol. Human beta-defensin-2

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Keywords: Human β-defensin-2, HβD-2; HBD-2 supplier, Anti-infection, inhibitors, activators

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