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HTT-D3 is a potent and orally active regulator of Huntington (HTT) splicing. HTT-D3 acts by promoting pseudo-exons containing the premature termination codon (psiExon), resulting in HTT mRNA degradation and reduced HTT levels. HTT-D3 reduces p-glycoprotein (P-gp) efflux and can be used in Huntington's disease research.
| Molecular Weight | 404.48 |
| Formula | C23H25FN6 |
| CAS Number | 2254502-89-9 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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