All AbMole products are for research use only, cannot be used for human consumption.
HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research.
| Molecular Weight | 419.52 |
| Formula | C24H29N5O2 |
| CAS Number | 2767422-72-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C) |
| Storage | Powder -20°C |
[3] Y Nishinaka-Kinoshita, et al. Hybridoma. Monoclonal antibodies against hst-1 gene product
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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