Free shipping on all orders over $ 500

HQNO

Cat. No. M20706

All AbMole products are for research use only, cannot be used for human consumption.

HQNO Structure
Synonym:

2-heptyl-4-hydroxyquinoline-N-oxide

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

HQNO is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione.

Chemical Information
Molecular Weight 259.34
Formula C16H21NO2
CAS Number 341-88-8
Solubility (25°C) DMSO 9 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiao Mo, et al. Int J Parasitol Drugs Drug Resist. Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo

[2] Jessica Petri, et al. Biochim Biophys Acta Bioenerg. Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

[3] Jiwon Kang, et al. J Biochem Mol Biol. HQNO-sensitive NADH:quinone oxidoreductase of Bacillus cereus KCTC 3674

[4] G Van Ark, et al. Biochim Biophys Acta. Binding of HQNO to beef-heart sub-mitochondrial particles

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.
Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.
NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.
Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.
Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.
  Catalog
Abmole Inhibitor Catalog




Keywords: HQNO, 2-heptyl-4-hydroxyquinoline-N-oxide supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.