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HMN-154 inhibits DNA binding of NF-Y to the human major histocompatibility complex class II human leukocyte antigen DRA Y-box sequence in a dose-dependent manner. HMN-154 inhibits KB and colon38 cells with IC50 values of 0.0026 and 0.003 μg/mL, respectively.
| Molecular Weight | 366.43 |
| Formula | C20H18N2O3S |
| CAS Number | 173528-92-2 |
| Solubility (25°C) | DMSO: ≥ 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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