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hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research.
| Molecular Weight | 320.4 |
| Formula | C20H16O2S |
| CAS Number | 1666119-75-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Monoamine Oxidase Products |
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Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
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Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. |
| Moclobemide
Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. |
| Nialamide
Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic. |
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