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Histamine is an endogenous ligand for histamine receptors, which can cause allergic reactions by interacting with H1 receptors, promote acid secretion by interacting with H2 receptors, as well as inhibit histamine release and modulate immune responses by interacting with H3 receptors and H4 receptors. It can be used in studies related to allergy, hyperacidity, sleep disorders, asthma and many other diseases.
| Molecular Weight | 111.15 |
| Formula | C5H9N3 |
| CAS Number | 51-45-6 |
| Solubility (25°C) | 34 mg/mL in water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histamine Receptor Products |
|---|
| Ciproxifan maleate
Ciproxifan is an orally bioavailable, extremely potent histamine H3 inverse agonist/antagonist. |
| Antazoline hydrochloride
Antazoline hydrochloride is a first generation antihistamine, binding to the histamine H1 receptor and blocking the action of endogenous histamine. |
| Azacyclonol
Azacyclonol, also known as γ-pipradol, which diminishes hallucinations in psychotic individuals. |
| Azatadine dimaleate
Azatadine dimaleate is an antihistamine and anticholinergic compound with IC50 of 6.5nM and 10nM, respectively. |
| Bepotastine Besilate
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7. |
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