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Helenalin acetate, a natural NF-κB inhibitor, is a potent C/EBPβ inhibitor. Helenalin acetate effectively inhibits C/EBPβ at least 10 times higher than that for NF-κB (EC50 values were determined between 0.1 and 0.4 μM for C/EBPβ). Helenalin acetate has anti-inflammatory and anticancer activities.
| Molecular Weight | 304.34 |
| Formula | C17H20O5 |
| CAS Number | 10180-86-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] J Malarz, et al. Planta Med. Helenalin Acetate in in vitro Propagated Plants of Arnica montana
| Related NF-κB Products |
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QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. QNZ (EVP4593) is a neuroprotective inhibitor of SOC channel. |
| Caffeic Acid Phenethyl Ester
Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
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| Methylthiouracil
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