hDHODH-IN-7

Cat. No. M54622

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hDHODH-IN-7 is a human dihydroorotic acid dehydrogenase (DHODH) inhibitor with concomitant antiviral activity and a pMIC50 of 7.4.

Molecular Weight	366.00
Formula	C21H23FN4O
CAS Number	1644156-41-1
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related DHODH Products
Leflunomide Leflunomide (HWA486) is an inhibitor of dihydroorotate dehydrogenase with IC50 of 2.5 μM.
Teriflunomide Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
Vidofludimus Vidofludimus (4SC-101; SC12267) is an immunosuppressant that inhibits DHODH and inhibits il-17 secretion without affecting lymphocyte proliferation.
Brequinar Brequinar is an effective Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 5.2 nM for human DHODH, and a broad-spectrum antiviral agent.
Orludodstat (BAY-2402234) BAY-2402234 is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies, with an IC50 of 1.2 nM.

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