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H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1, which promotes cell adhesion, neurite growth, and tumor growth. It also stimulates BMSC cell growth and proliferation and proliferating cell nuclear antigen (PCNA) synthesis by activating the MAPK/ERK1/2 and PI3K/Akt signaling pathways.
| Molecular Weight | 528.69 |
| Formula | C25H48N6O6 |
| CAS Number | 131167-89-0 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] D D Vandré et al. Biochemistry. Largomycin: preparation, properties, and structure
[3] Y Mizuno et al. J Biochem. Amino acid sequence of acylphosphatase from porcine skeletal muscle
[4] D J Strydom et al. Biochemistry. Amino acid sequence of human tumor derived angiogenin
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