All AbMole products are for research use only, cannot be used for human consumption.
Gyki-52466 is a 2, 3-bendiazepine compound. As an ionic glutamate receptor antagonist, gyki-52466 is a non-competitive AMPA receptor antagonist (IC50 values of AMPA-, Kainate - and NMDA induced responses are 10-20, ~450 and >>50 μM, respectively). Oral active anticonvulsant compounds and skeletal muscle relaxation compounds. Unlike conventional 4, 5-benzodiazepines, Gyki-52466 and related 2, 3-benzodiazepines do not act on gabA-A receptors. Like other AMPA receptor antagonists, GYki-52466 has anticonvulsant and neuroprotective properties.
| Molecular Weight | 293.32 |
| Formula | C17H15N3O2 |
| CAS Number | 102771-26-6 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GluR Products |
|---|
| AZD6765
AZD6765 is an NMDA receptor antagonist. |
| LY404039
LY404039 is a potent, selective and orally active agonist of recombinant human mGlu2, mGlu3 receptors with Ki of 149 nM, 92 nM respectively. |
| Felbamate
Felbamate(Felbatol) is an anticonvulsant compound used in epilepsy research. |
| CTEP
CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors. |
| VU 0361737
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
