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GW 542573X is a activator of small-conductance Ca2+-activated K+ channels (KCa2); selective for KCa2.1 (EC50 = 8.2 μM in HEK293 cells expressing hKCa2.1) with the profile hKCa2.1 > hKCa2.2 = hKCa2.3 > hKCa3.1 (IK).
| Molecular Weight | 364.44 |
| Formula | C19H28N2O5 |
| CAS Number | 660846-41-3 |
| Solubility (25°C) | DMSO 36.44 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Ruben, et al. RNA. Thiostrepton inhibition of tRNA delivery to the ribosome.
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