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Guanosine 3′,5′-cyclic monophosphate (cGMP) acts as an important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
| Molecular Weight | 345.21 |
| Formula | C10H12N5O7P |
| CAS Number | 7665-99-8 |
| Solubility (25°C) | 0.2 M NaHCO3: 50 mg/mL |
| Storage | -20°C, dry, sealed |
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