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GTP-14564

Cat. No. M43513

All AbMole products are for research use only, cannot be used for human consumption.

GTP-14564 Structure

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Quality Control & Documentation
Biological Activity

GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3.

Chemical Information
Molecular Weight 234.25
Formula C15H10N2O
CAS Number 34823-86-4
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Q Yao et al. Leukemia. Human leukemias with mutated FLT3 kinase are synergistically sensitive to FLT3 and Hsp90 inhibitors: the key role of the STAT5 signal transduction pathway

[2] Ken Murata et al. J Biol Chem. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3)

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  Catalog
Abmole Inhibitor Catalog




Keywords: GTP-14564 supplier, FLT3, inhibitors, activators

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