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GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used for the research of microsatellite instability-high (MSI-H) cancer.
| Molecular Weight | 646.65 |
| Formula | C31H30F4N4O5S |
| CAS Number | 3064599-36-3 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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