All AbMole products are for research use only, cannot be used for human consumption.
GSK3987 is a pan LXRα/β agonist with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation.
| Molecular Weight | 384.43 |
| Formula | C24H20N2O3 |
| CAS Number | 264206-85-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[2] Hsiang-Ru Lin. J Asian Nat Prod Res. Paeoniflorin acts as a liver X receptor agonist
| Related Liver X Receptor Products |
|---|
| GW3965 hydrochloride
GW3965 hydrochloride is a selective, orally active non-steroidal synthetic liver X receptor (LXR) agonist. |
| T0901317
T0901317 is a potent and selective agonist for both LXRα and LXRβ with an EC50 of 20~50 nM. T0901317 activates FXR with an EC50 of 5 μM. T0901317 is RORα and RORγ dual inverse agonist with Ki values of 132 nM and 51 nM, respectively. |
| SR9243
SR9243 is a potent and selective LXR inverse agonist. |
| LXR-623
LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier. |
| GSK2033
GSK2033 is a potent LXR antagonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
