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GSK3735967 is an selective, reversible, non-nucleoside inhibitor of DNMT1 with an IC50 value of 40 nM.
| Molecular Weight | 477.62 |
| Formula | C25H31N7OS |
| CAS Number | 2170136-86-2 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage | Powder -20°C |
| Related DNA Methyltransferase Products |
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Decitabine (5-Aza-2'-deoxycytidine) is a potent inhibitor of DNA methylation for the treatment of myelodysplastic syndromes. |
| RG108
RG108 is a novel small-molecule inhibitors of DNA methyltransferases with IC50 of 115 nM. |
| Lomeguatrib
Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM. |
| SGI-1027
SGI-1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B |
| SGI-110
SGI-110 (S-110) is a stable and potent inhibitor for DNA methylation, inhibits DNMT1 when SGI-110 is activated by phosphorylation and incorporated into DNA. |
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