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GSK1521498 is a potent and selective μ-opioid receptor antagonist. GSK1521498 dose-dependently reduced both cue-controlled alcohol seeking and alcohol intake in the instrumental context as well as alcohol intake in the choice procedure.
| Molecular Weight | 402.44 |
| Formula | C24H20F2N4 |
| CAS Number | 1007573-18-3 |
| Solubility (25°C) | DMSO ≥ 6 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Opioid Receptor Products |
|---|
| ADL5859 Hydrochloride
ADL5859 is a potent, selective and orally bioavailable δ-opioid receptor agonist (Ki = 0.84 nM, EC50 = 20 nM). |
| JTC-801
JTC-801 is a novel opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM. |
| Meptazinol hydrochloride
Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM. |
| Nalmefene hydrochloride
Nalmefene is an opioid receptor antagonist, it is used primarily in the management of alcohol dependence. |
| Naloxone hydrochloride
Naloxone hydrochloride is an opioid inverse agonist compound used to counter the effects of opiate overdose. |
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