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GS87 is a highly specific GSK3 (glycogen synthase kinase 3) inhibitor that induces extensive differentiation of AML cells. GS87 potently inhibits growth of AML cells in mice with little effect on normal bone marrow cells. GS87 causes terminal differentiation of AML cells.
| Molecular Weight | 337.36 |
| Formula | C16H11N5O2S |
| CAS Number | 919936-70-2 |
| Solubility (25°C) | DMSO: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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