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Groenlandicine

Cat. No. M4403

All AbMole products are for research use only, cannot be used for human consumption.

Groenlandicine Structure
Size Price Availability Quantity
10mg USD 480 In stock
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Quality Control & Documentation
Biological Activity

Groenlandicine is a proto berberine alkaloid isolated from coptis chinensis. Groenlandicine has moderate inhibition of human recombinant aldose reductase (HRAR) with an IC50 value of 154.2 μM. Groenlandicine induces DNA cleavage mediated by topoisomerase I.

Chemical Information
Molecular Weight 322.33
Formula C19H16NO4+
CAS Number 38691-95-1
Storage 4°C, protect from light, dry, sealed
References

[1] Tao Li, et al. Screening of quantitative preparation quality markers of Yulian Decoction

[2] Xu Yin, et al. Chemical constituents from a Tibetan herbal medicine Corydalis hendersonii

[3] Hong-Ying Chen, et al. Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma Coptis in HepG2 cells

[4] Hyun Ah Jung, et al. Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids

[5] Hyun Ah Jung, et al. Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase

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Keywords: Groenlandicine supplier, Topoisomerase, inhibitors, activators

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