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GPNA hydrochloride

Cat. No. M13509

All AbMole products are for research use only, cannot be used for human consumption.

GPNA hydrochloride Structure
Size Price Availability Quantity
10mg USD 50 In stock
50mg USD 149 In stock
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Quality Control & Documentation
Biological Activity

GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells.

Chemical Information
Molecular Weight 303.7
CAS Number 67953-08-6
Solubility (25°C) DMSO 90 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Jiamin Wu, et al. Mol Pharm. A Glutamine-Rich Carrier Efficiently Delivers Anti-CD47 siRNA Driven by a "Glutamine Trap" To Inhibit Lung Cancer Cell Growth

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Keywords: GPNA hydrochloride supplier, Apoptosis, inhibitors, activators

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