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GPLGIAGQ TFA is a MMP2-cleavable polypeptide, used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.
GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).
Sequence: Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
| Molecular Weight | 825.83 |
| Formula | C33H54F3N9O12 |
| CAS Number | 109053-09-0 (free base) |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | Store at ≤-20°C, dry, sealed |
| Related MMP Products |
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| NSC 405020
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| Marimastat
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