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GNF6702 

Cat. No. M28866

All AbMole products are for research use only, cannot be used for human consumption.

GNF6702  Structure

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Quality Control & Documentation
Biological Activity

GNF6702 is a selective inhibitor of the kinetoplastid proteasome. GNF6702 clears parasites in murine models of leishmaniasis, Chagas disease, and human African trypanosomiasis.

Chemical Information
Molecular Weight 429.41
Formula C22H16FN7O2
CAS Number 1799329-72-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Srinivasa P S Rao, et al. Trop Med Infect Dis. Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

[2] Alane Beatriz Vermelho, et al. Expert Opin Drug Discov. Why hasn't there been more progress in new Chagas disease drug discovery?

[3] Patrícia de Almeida Machado, et al. Life Sci. Leishmanicidal therapy targeted to parasite proteases

[4] Shilpi Khare, et al. Nature. Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

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Abmole Inhibitor Catalog




Keywords: GNF6702  supplier, Parasite, inhibitors, activators

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