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GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
| Molecular Weight | 467.78 |
| Formula | C16H8ClF6N5OS |
| CAS Number | 1883518-31-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 190 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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