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Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).
| Molecular Weight | 656.17 |
| CAS Number | 1123838-51-6 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
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