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GGTI-2417

Cat. No. M43524

All AbMole products are for research use only, cannot be used for human consumption.

GGTI-2417 Structure

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Biological Activity

GGTI-2417 is a potent and selective inhibitor of GGTase I.

Chemical Information
Molecular Weight 455.55
Formula C24H33N5O4
CAS Number 501010-05-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Aslamuzzaman Kazi et al. Mol Cell Biol. Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy

[2] Samuel C Falsetti et al. Mol Cell Biol. Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth

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Keywords: GGTI-2417 supplier, ROS Kinase, inhibitors, activators

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