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Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II).
| CAS Number | 1129435-60-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] Wen-Ming Wang, et al. Expert Opin Drug Saf. Biologics in the treatment of pustular psoriasis
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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