All AbMole products are for research use only, cannot be used for human consumption.
Genistein is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Genistein also binds to PPARγ and estrogen receptors and acts as an agonist at GPR30.
Biomaterials. 2021 Aug;275:120958.
Tumor progress intercept by intervening in Caveolin-1 related intercellular communication via ROS-sensitive c-Myc targeting therapy
Genistein purchased from AbMole
| Molecular Weight | 270.24 |
| Formula | C15H10O5 |
| CAS Number | 446-72-0 |
| Solubility (25°C) | DMSO 54 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Linda Yu, et al. Genistein: Dual Role in Women's Health
[3] Neha Jaiswal, et al. An Overview on Genistein and its Various Formulations
[4] Vidya Mukund, et al. Genistein: Its role in metabolic diseases and cancer
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