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Gemcitabine elaidate

Cat. No. M13701

All AbMole products are for research use only, cannot be used for human consumption.

Gemcitabine elaidate Structure
Synonym:

CP-4126; CO-101; Gemcitabine 5'-elaidate

Price and Availability

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Quality Control & Documentation
Biological Activity

Gemcitabine elaidate (CP-4126) is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate exhibits anti-tumor activity.

Chemical Information
Molecular Weight 527.64
CAS Number 210829-30-4
Solubility (25°C) DMSO ≥ 26 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bowen Sun, et al. Adv Sci (Weinh). Wirelessly Activated Nanotherapeutics for In Vivo Programmable Photodynamic-Chemotherapy of Orthotopic Bladder Cancer

[2] Godefridus J Peters. Nucleosides Nucleotides Nucleic Acids. Novel developments in the use of antimetabolites

[3] Andries M Bergman, et al. Invest New Drugs. Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models

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Keywords: Gemcitabine elaidate, CP-4126; CO-101; Gemcitabine 5'-elaidate supplier, inhibitors, activators

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