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GDC-0310

Cat. No. M21126

All AbMole products are for research use only, cannot be used for human consumption.

GDC-0310 Structure

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Quality Control & Documentation
Biological Activity

GDC-0310 is a selective Nav1.7 acyl sulfonamide inhibitor with an IC50 value of 0.6 nM for hNav1.7. It is an oral primary clinical candidate for the study of pain.

Chemical Information
Molecular Weight 543.48
Formula C25H29Cl2FN2O4S
CAS Number 1788063-52-4
Solubility (25°C) DMSO : 4 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brian S Safina, et al. J Med Chem. Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310

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Keywords: GDC-0310 supplier, Sodium Channel, inhibitors, activators

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