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GB-110 

Cat. No. M28044

All AbMole products are for research use only, cannot be used for human consumption.

GB-110  Structure

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Quality Control & Documentation
Biological Activity

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.

Chemical Information
Molecular Weight 608.77
Formula C33H48N6O5
CAS Number 1252806-70-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Kelsey Shields, et al. Anaerobe. Recurrent Clostridium difficile infection: From colonization to cure

[2] Kavita Kumari Kakarala, et al. J Mol Graph Model. Structure and putative signaling mechanism of Protease activated receptor 2 (PAR2) - a promising target for breast cancer

[3] J Y Suen, et al. Br J Pharmacol. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)

[4] Grant D Barry, et al. J Med Chem. Novel agonists and antagonists for human protease activated receptor 2

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  Catalog
Abmole Inhibitor Catalog




Keywords: GB-110  supplier, PAR, inhibitors, activators

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