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Gartanin

Cat. No. M19413

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Gartanin Structure

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Quality Control & Documentation
Biological Activity

Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.

Chemical Information
Molecular Weight 396.43
Formula C23H24O6
CAS Number 33390-42-0
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R A Oetari, et al. Open Access Maced J Med Sci. Gartanin Compounds from Extract Ethanol Pericarp Mangosteen ( Garcinia mangostana Linn.)

[2] Victor Pham, et al. Mol Carcinog. Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy

[3] Ming Luo, et al. J Cell Mol Med. Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells

[4] Xiao-Yun Gao, et al. Neurochem Res. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK

[5] Mun-Ock Kim, et al. Oncol Rep. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis

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Keywords: Gartanin supplier, Antifungal, inhibitors, activators

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