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Garcinol is a kind of polyisoprene diphenylketone extracted from Garcinia japonicum. It has anticholinesterase properties for AChE and butyrylcholinesterase (BChE) with IC50 of 0.66 µM and 7.39 µM, respectively. Garcinol also inhibited histone acetyltransferases (HATs, IC50=7 μM) and P300 /CPB related factors (PCAF, IC50=5 μM). Garcinol has anti-inflammatory and anticancer activities.
| Molecular Weight | 602.8 |
| Formula | C38H50O6 |
| CAS Number | 78824-30-3 |
| Solubility (25°C) | DMSO 45 mg/mL Ethanol 20 mg/mL |
| Storage | -20°C, dry, sealed |
[2] Se In Son, et al. ACS Chem Biol. Garcinol Is an HDAC11 Inhibitor
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