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Galectin-3/galectin-8-IN-2 is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 12.8 μM and 2.06 μM respectively.
| Molecular Weight | 557.47 |
| Formula | C26H18Cl2N2O4S2 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Szu-Chia Chen et al. Int J Mol Sci. The Role of Galectin-3 in the Kidneys
| Related Galectin Products |
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GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM. GB1107 inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade. GB1107 potentiates the effects of a PD-L1 immune checkpoint inhibitor to increase expression of cytotoxic (IFN-γ, granzyme B, perforin-1, Fas ligand) and apoptotic (cleaved caspase-3) effector molecules. |
| OTX008
OTX008 is a selective inhibitor of galectin-1. |
| G3-C12
G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. |
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