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Galanthaminone

Cat. No. M30214

All AbMole products are for research use only, cannot be used for human consumption.

Galanthaminone Structure
Synonym:

(-)-Narwedine; Narwedin

Size Price Availability Quantity
1mg USD 50 In stock
5mg USD 110 In stock
10mg USD 170 In stock
25mg USD 310 In stock
50mg USD 440 In stock
100mg USD 640 In stock
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Quality Control & Documentation
Biological Activity

Galanthaminone (Narwedin) is a competitive and reversible cholinesterase (AChE) inhibitor; is used for the research of mild to moderate Alzheimer's disease and various other memory impairments.

Chemical Information
Molecular Weight 285.34
Formula C17H19NO3
CAS Number 510-77-0
Form Solid
Solubility (25°C) DMSO 10 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] J KOIZUMI, et al. Chem Pharm Bull (Tokyo). GALANTHAMINE CHEMISTRY. V. FORMATION OF HYDROXYAPOGALANTHAMINE FROM GALANTHAMINONE AND THE SYNTHESIS OF ITS TRIMETHYL ETHER

[2] D Mihailova, et al. Eur J Drug Metab Pharmacokinet. In vitro metabolism of galanthamine hydrobromide (Nivalin) by rat and rabbit liver homogenate

[3] D Mihailova, et al. Pharmacology. Pharmacokinetics of galanthamine hydrobromide after single subcutaneous and oral dosage in humans

[4] T Thomsen, et al. Eur J Clin Pharmacol. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans

[5] U Bickel, et al. Clin Pharmacol Ther. Pharmacokinetics of galanthamine in humans and corresponding cholinesterase inhibition

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Keywords: Galanthaminone, (-)-Narwedine; Narwedin supplier, AChR/AChE, inhibitors, activators

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