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Fumarate hydratase-IN-1

Cat. No. M22353

All AbMole products are for research use only, cannot be used for human consumption.

Fumarate hydratase-IN-1 Structure
Size Price Availability Quantity
2mg USD 165 In stock
5mg USD 260 In stock
10mg USD 360 In stock
25mg USD 720 In stock
50mg USD 1120 In stock
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Quality Control & Documentation
Biological Activity

Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.

Chemical Information
Molecular Weight 446.54
Formula C27H30N2O4
CAS Number 1644060-37-6
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Irena Majkutewicz. Eur J Pharmacol. Dimethyl fumarate: A review of preclinical efficacy in models of neurodegenerative diseases

[2] Julia Paik. CNS Drugs. Diroximel Fumarate in Relapsing Forms of Multiple Sclerosis: A Profile of Its Use

[3] Duvyanshu Dubey, et al. Expert Rev Neurother. Dimethyl fumarate in relapsing-remitting multiple sclerosis: rationale, mechanisms of action, pharmacokinetics, efficacy and safety

[4] Take-Aki Mitsudo, et al. Chem Rec. Chemistry of Ru(eta6-1,3,5-cyclooctatriene)(eta2-dimethyl fumarate)2

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Keywords: Fumarate hydratase-IN-1 supplier, Mitochondrial Related, inhibitors, activators

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