All AbMole products are for research use only, cannot be used for human consumption.
Fresolimumab (GC1008) is a high-affinity fully human monoclonal antibody that neutralizes the active form of human TGFβ1, TGFβ2, and TGFβ3. Fresolimumab can be used for the research of cancer and fibrotic diseases .
| CAS Number | 948564-73-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] I-Wen Song, et al. J Clin Invest. Targeting TGF-β for treatment of osteogenesis imperfecta
[3] Beverly A Teicher. Pharmacol Ther. TGFβ-Directed Therapeutics: 2020
[4] Yoshitaka Isaka. Int J Mol Sci. Targeting TGF-β Signaling in Kidney Fibrosis
| Related TGF-beta/Smad Products |
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| Pirfenidone
Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells. Pirfenidone (AMR69) attenuates CCL2 and CCL12 production in fibrocyte cells. |
| Asiaticoside
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. |
| Amygdalin
Laetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds. |
| Norcantharidin
Norcantharidin |
| Kartogenin
Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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