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FR181157

Cat. No. M41907

All AbMole products are for research use only, cannot be used for human consumption.

FR181157 Structure

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Quality Control & Documentation
Biological Activity

FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties.

Chemical Information
Molecular Weight 487.52
Formula C30H26NNaO4
CAS Number 171046-15-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Akira Tanaka et al. Bioorg Med Chem Lett. Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: orally active prostacyclin mimetics. Part 6

[2] Kouji Hattori et al. Bioorg Med Chem Lett. Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4

[3] Kouji Hattori et al. Bioorg Med Chem Lett. A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic

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Keywords: FR181157 supplier, Prostaglandin Receptor, inhibitors, activators

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