All AbMole products are for research use only, cannot be used for human consumption.
Folic acid is an adjuvant compound used in cancer chemotherapy.
*The compound is unstable in solutions, freshly prepared is recommended
PLoS One. 2020 May 18;15(5):e0231588.
Patient-derived Oral Mucosa Organoids as an in Vitro Model for Methotrexate Induced Toxicity in Pediatric Acute Lymphoblastic Leukemia
Folinic acid calcium salt purchased from AbMole
| Molecular Weight | 511.50 |
| Formula | C20H21N7O7.Ca |
| CAS Number | 1492-18-8 |
| Solubility (25°C) | Water ≥ 50 mg/mL |
| Storage | 4°C, dry, protect from light, sealed |
[2] Shuna Sun, et al. Effects of methotrexate on the developments of heart and vessel in zebrafish
[4] A G De Michelis, et al. The calcium salt of folinic acid for the treatment of deficiency anemia
| Related Antifolate Products |
|---|
| Pemetrexed disodium
Pemetrexed is a novel antifolic acid antimetabolic compound with K I of 1.3 nM, 7.2 nM, and 65 nM for TS, DHFR, and GARFT, respectively. |
| Methotrexate
Methotrexate (Amethopterin) is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. |
| Sulfamethazine
Sulfamethazine is a sulfonamide antibacterial. |
| Pyrimethamine
Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM. |
| Methotrexate metabolite
Methotrexate metabolite is a dihydrofolate reductase potent inhibitor with an IC50 of 1 nM. |
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