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FMF-04-159-2 

Cat. No. M29539

All AbMole products are for research use only, cannot be used for human consumption.

FMF-04-159-2  Structure

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Quality Control & Documentation
Biological Activity

FMF-04-159-2 is a covalent CDK14 inhibitor. FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively.

Chemical Information
Molecular Weight 683.01
Formula C28H30Cl3N7O5S
CAS Number 2364489-81-4
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mengna Zhang, et al. Cell Rep. CDK14 inhibition reduces mammary stem cell activity and suppresses triple negative breast cancer progression

[2] Fleur M Ferguson, et al. Bioorg Med Chem Lett. Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14

[3] Fleur M Ferguson, et al. Cell Chem Biol. Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

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  Catalog
Abmole Inhibitor Catalog




Keywords: FMF-04-159-2  supplier, CDK, inhibitors, activators

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