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Fluxametamide

Cat. No. M22324

All AbMole products are for research use only, cannot be used for human consumption.

Fluxametamide Structure
Size Price Availability Quantity
5mg USD 85 In stock
10mg USD 138 In stock
25mg USD 270 In stock
50mg USD 410 In stock
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Quality Control & Documentation
Biological Activity

Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 values of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. Fluxametamide shows significant insecticidal activity with an LD50 (LD95) value of 12.9 ± 4.9 ng/fly (38.7 ± 6.3 ng/fly).

Chemical Information
Molecular Weight 474.26
Formula C20H16Cl2F3N3O3
CAS Number 928783-29-3
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Debashis Roy, et al. Toxics. Risk Assessment of Fluxametamide Resistance and Fitness Costs in Fall Armyworm ( Spodoptera frugiperda)

[2] Qiutang Huang, et al. Environ Pollut. The acute toxicity, mechanism, bioconcentration and elimination of fluxametamide on zebrafish (Danio rerio)

[3] Food Safety Commission of Japan. Food Saf (Tokyo). Fluxametamide (Pesticides)

[4] Runan Li, et al. Environ Sci Technol. Development of S-Fluxametamide for Bioactivity Improvement and Risk Reduction: Systemic Evaluation of the Novel Insecticide Fluxametamide at the Enantiomeric Level

[5] Miho Asahi, et al. Pestic Biochem Physiol. Fluxametamide: A novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels

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